The combination of multiband EPI with in-plane parallel imaging yields a total acceleration factor AF=MB*R, MB and R representing the slice and in-plane acceleration factors, respectively. The data quality of T2*-weighted and diffusion-weighted imaging was compared for different AF, using different combinations of MB and R, and for different head coils, providing advice on the optimum experimental set-up. Results suggest that severe artifacts may occur for large MB and R, a low number of slices (SL) and head coils with a reduced number of elements (NE). Suggestions comprise SL≥48, NE≥32, MB≤8 and R≤4.
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