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Abstract #3963

Post-surgical human brain functional reorganization in gliomas: a longitudinal study

Francesca Saviola1, Lisa Novello1, Domenico ZacĂ 1,2, Luciano Annicchiarico3,4, Luca Zigiotto3,4, Silvio Sarubbo3,4, and Jorge Jovicich1
1CIMeC, Center for Mind/Brain Sciences, University of Trento, Rovereto, Italy, 2Siemens Healthcare, Milano, Italy, 3Department of Neuroscience,, Division of Neurosurgery, S.Chiara Hospital, Trento, Italy, 4Structural and Functional Connectivity Lab, S.Chiara Hospital, Trento, Italy

The recent brain connectomic framework has introduced a shift in the study of brain tumors. Previously considered as a focal brain disease, brain tumors are nowadays also studied in the context of structural and functional neural networking disruptions and their cognitive consequences. In this longitudinal behavior and resting state functional MRI study, we investigate how tumor grade, behavior and functional connectivity in brain network hubs and their connections to non-hubs are affected following surgical tumor resection.

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