Migraine is a severe neurological brain condition of cyclical nature, with intermittent attacks alternating with attack-free periods. In this work, we studied a group of patients with episodic migraine without aura during a spontaneous migraine attack and during a pain-free period, using BOLD resting-state fMRI. Results showed decreases in functional connectivity (FC) within a sensorimotor-insular cortex network and a left frontoparietal/executive control network. These FC changes were correlated with the attack duration and the pain intensity of the ongoing attack, respectively.
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