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Abstract #3997

Surface-Based Morphometry of Brain in Benign Childhood Epilepsy with Centrotemporal Spikes

Zhengzhen Li1, Lisha Nie2, Xiaoxi Chen1, Heng Liu1, and Tijiang Zhang1
1Medical Imaging, the Affiliated Hospital of Zunyi Medical University, Zunyi, China, 2GE Healthcare,MR Research China, Beijing, China

This study investigated the cortical morphological changes of drug-naïve Benign childhood epilepsy with centrotemporal spikes (BECTS) using three-dimensional T1- weighted images(3D-T1WI) and explored the possible influence of cortical morphological changes on cognition.The results revealed aberrant morphology in thickness, gyrification and fractal dimension, in addition to Rolandic region. Cortical gyrification of right parahippocampal gyrus in BECTS may indirectly reflect the degree of language transmission damage or the result of contralateral compensation.

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