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Abstract #4011

Comparison of Phase Synchrony Analysis and Pearson’s Correlation Coefficient in Resting State fMRI of Rat Brain

Yi-Cheng Wang1, Chia-Yu Huang1, Wen-Yen Chai2, Mey-Yu Yeh1, Hao-Li Liu2, and Fu-Nien Wang1
1National Tsing Hua University, Hsinchu, Taiwan, 2Chang Gung University, Taoyuan, Taiwan

Phase synchrony has been considered as an alternative method to measure connectivity in resting state functional MRI. Our results showed that the data with the correlation coefficient are monotonically increasing, but only when the correlation coefficient is larger than 0.4, phase synchrony and correlation coefficient showed linear dependence. The mappings of default mode network based on two analysis methods are similar in rat brains. However, care should be taken when interpreting data with lower phase synchrony (<0.4), since the phase synchrony of noise is also distributed in the range.

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