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Abstract #4145

4D-MRI of Thorax and Abdomen with Variable Contrast at 1.5T

Orso Andrea Pusterla1,2,3, Francesco Santini2,3, Grzgorz Bauman2,3, Rahel Heule4, Alina Giger3, Philippe Claude Cattin3, Sairos Safai5, Sebastian Kozerke1, and Oliver Bieri2,3
1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, 2Department of Radiology, Division of Radiological Physics, University Hospital Basel, Basel, Switzerland, 3Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland, 4High Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 5Center for Proton Therapy, Paul Scherrer Institute, Villigen-PSI, Switzerland

Time-resolved volumetric imaging (4D-MRI) of moving organs is essential for several clinical applications, e.g., in interventional treatments, radiation therapies, and high-intensity focused ultrasound ablations. In this work, an interleaved time-resolved data-navigator acquisition strategy for 4D-MRI with flexible contrast is developed offering versatile settings for thoracic and abdominal imaging: for both, image and navigator, not only the flip angle but also the basic acquisition type (pulse sequence kernel) can be chosen independently from either balanced SSFP (i.e., T2/T1-weighted) or spoiled gradient echo (i.e., T1-weighted).

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