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Abstract #4155

A test-retest analysis of motion compensation in image-guided radiation therapy using hands-free simultaneous MR-U/S system.

Jhimli Mitra1, Sydney Jupitz2, Bryan Bednarz2, James H. Holmes3, David Mills1, Lowell Scott Smith1, Heather Chan1, Aqsa Patel1, Eric Fiveland1, Warren Lee1, Alan McMillan3, Wes Culberson2, Michael Bassetti4, Andrew Shepard2, Shourya Sarcar1, and Thomas K. Foo1
1General Electric Research, Niskayuna, NY, United States, 2Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, 3Radiology, University of Wisconsin - Madison, Madison, WI, United States, 4Human Oncology, University of Wisconsin - Madison, Madison, WI, United States

An MR-compatible ultrasound probe was developed for hands-free, simultaneous MR-ultrasound image acquisition for image-guided radiation therapy in liver. Simultaneously acquired pre-treatment MR and U/S associates a pair of MR image and U/S volume to each respiratory state over multiple respiratory cycles without requiring physical MR image acquisition during the radiation treatment LINAC phase. Automatic fiducial tracking and respiratory state clustering were performed on the U/S volumes to determine expiration states for dose delivery. In a test-retest analysis, consistent and reproducible expiration states were obtained that can be used for targeted-dose delivery under LINAC.

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