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Abstract #4230

Numerical optimization of an iPRES coil design for high SNR and localized B0 shimming performance in small animal imaging

Zack Thompson1,2, Dean Darnell1,2, Darya Morozov3, Scott C Beeman3,4, Allen W Song1,2, and Trong-Kha Truong1,2
1Medical Physics Graduate Program, Duke University, Durham, NC, United States, 2Brain Imaging and Analysis Center, Duke University, Durham, NC, United States, 3Biomedical Magnetic Resonance Laboratory, Washington University in St. Louis, St. Louis, MO, United States, 4School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States

Susceptibility-induced B0 inhomogeneities can cause distortions and signal loss, which are exacerbated in small animal imaging due to the typically higher field strength and smaller anatomy. Here, we further develop the integrated parallel reception, excitation, and shimming (iPRES) coil technology, which enables imaging and localized B0 shimming with a single RF/shim coil array, for small animal imaging. We start by numerically optimizing the design of a 4-channel iPRES rat coil array to achieve both a high B0 shimming performance (54.2% reduction in B0 root-mean-square error) and a high and uniform SNR over the brain.

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