Abstract #4230

Numerical optimization of an iPRES coil design for high SNR and localized B0 shimming performance in small animal imaging

Zack Thompson^1,2, Dean Darnell^1,2, Darya Morozov³, Scott C Beeman^3,4, Allen W Song^1,2, and Trong-Kha Truong^1,2

¹Medical Physics Graduate Program, Duke University, Durham, NC, United States, ²Brain Imaging and Analysis Center, Duke University, Durham, NC, United States, ³Biomedical Magnetic Resonance Laboratory, Washington University in St. Louis, St. Louis, MO, United States, ⁴School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States

Susceptibility-induced B₀ inhomogeneities can cause distortions and signal loss, which are exacerbated in small animal imaging due to the typically higher field strength and smaller anatomy. Here, we further develop the integrated parallel reception, excitation, and shimming (iPRES) coil technology, which enables imaging and localized B₀ shimming with a single RF/shim coil array, for small animal imaging. We start by numerically optimizing the design of a 4-channel iPRES rat coil array to achieve both a high B₀ shimming performance (54.2% reduction in B₀ root-mean-square error) and a high and uniform SNR over the brain.

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