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Abstract #4303

Simultaneous Acquisition of Dynamic Diffusion Imaging and Diffusion Tensor Imaging in the Brain

Mihika Gangolli1, Wen-Tung Wang1, Neville Gai2, Dzung L. Pham1, and John Butman1,2
1Center for Neuroscience and Regenerative Medicine, Bethesda, MD, United States, 2National Institutes of Health, Bethesda, MD, United States

We propose a diffusion acquisition scheme, called “nested cubes”, consisting of five triplets of three unique mutually orthogonal directions, providing diffusion weighted data sampled across fifteen noncollinear directions distributed uniformly across a spherical shell. Data acquired using this setup facilitates the simultaneous acquisition of dynamic maps of trace and other diffusion metrics while producing DTI measurements comparable to those from a standard DTI sequence.

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