Rotation invariant features can potentially be used as biomarkers for diffusion MRI. One of the most important characteristics of biomarkers is their reproducibility. In the case of diffusion MRI, reproducibility means that if we acquire data from the same subject twice with a short time gap between the two acquisitions we should obtain the same values for the biomarkers. In this work, we investigate the reproducibility of 12 new rotation invariant features that we obtained from 4th order spherical harmonics. Our results suggest that the new invariants are reproducible and can be selected as biomarker-candidates for white matter.
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