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Abstract #4321

Optimal experimental design for multi-tissue spherical deconvolution of diffusion MRI

Jan Morez1, Jan Sijbers1, and Ben Jeurissen1
1imec-Vision Lab, Dept. Physics, University of Antwerp, Antwerp, Belgium

Multi-tissue constrained spherical deconvolution of multi-shell diffusion weighted MRI data estimates the white matter fiber orientation distribution function, together with the densities of gray matter and cerebrospinal fluid. In this work, we propose a 5-minute scanning protocol that allows a more precise estimation of WM and GM densities, while maintaining a high angular resolution.

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