Abstract #4399

Using Diffusional Kurtosis Imaging to Quantify non-Gaussian Water Diffusion in Normal Human Liver

Junying Wang¹, Hansen Schie², Weiqiang Dou³, and Xiaoyi He¹

¹Medical Imaging, Shandong First Medical University, Jinan, Shandong, China, China, ²Medical Imaging, Shandong Provincial Qianfoshan Hospital，the First Hospital Affiliated with Shandong First Medical University, Jinan City, Shandong Province, China, China, ³GE Healthcare, MR Research China,Bejing, Bejing,China, China

This study aimed to test the reproducibility of DKI technique in normal liver and to explore the microscopic and diffusion differences between the left and right hepatic lobes.

32 healthy volunteers were scanned in DKI twice and the interval time was two weeks. All DKI-derived parametrical maps were reconstructed and mean values in eight liver segments were calculated.

We demonstrated that DKI in the liver showed excellent reproducibility between two measurements and found interesting regional distributions of the parameters in liver. Additionally, significant difference was found in DKI-derived parameters between the left and right hepatic lobes

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