Meeting Banner
Abstract #4434

On the bias introduced by assuming different intravoxel incoherent motion regimes

Oscar Jalnefjord1,2, Nicolas Geades3, and Maria Ljungberg1,2
1Department of Radiation Physics, University of Gothenburg, Gothenburg, Sweden, 2Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden, 3Philips Clinical Science, Gothenburg, Sweden

Intravoxel incoherent motion (IVIM) analysis typically assumes that the motion of blood caused by microcirculation mimics a random walk with several steps taken during the diffusion encoding (diffusive regime). Some studies have suggested use of the other extreme regime where no direction changes occur during diffusion encoding (ballistic regime). However, data available suggest that an intermediate regime is more likely. In this study, we explore the impact of assuming different IVIM regimes on modeling and parameter estimation. Results on healthy liver indicate that substantial bias may be introduced unless proper modeling is used.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here