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Abstract #4502

Double-Diffusion-Encoding MRI: phantom evaluation of concomitant gradient effects with single- and twice-refocused sequences

Lisa Novello1, Stefano Tambalo1, Thorsten Feiweier2, and Jorge Jovicich1
1CIMeC, Center for Mind/Brain Sciences, University of Trento, Rovereto, Italy, 2Siemens Healthcare GmbH, Erlangen, Germany

In Double-Diffusion-Encoding sequences, concomitant gradients may introduce spatial bias in the measured MRI signal. It is important to characterize such biases since they can affect the accuracy of quantitative microstructural metrics in brain studies. In this work, we assess the signal deviations at different positions along the scanner z-axis in an isotropic phantom for both single- and twice-refocused spin-echo sequences.

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