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Abstract #4532

High-resolution Distortion-free DWI of Pituitary Adenomas and Rathke Cleft Cysts Using Point-spread-function Encoded EPI

Jieying Zhang1, Chunjie Guo2, Xinrui Liu3, Yishi Wang1,4, Huimao Zhang2, and Hua Guo1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Department of Radiology, the First Hospital of Jilin University, Changchun, China, 3Department of Neurosurgery, the First Hospital of Jilin University, Changchun, China, 4Philips Healthcare, Beijing, China

Differentiation between pituitary adenomas (PAs) and Rathke cleft cysts (RCCs) is important for treatment planning. Diffusion weighted imaging (DWI) has been reported for the differentiation. However, traditional single-shot echo planar imaging (EPI) DWI has limited resolution and suffers from image distortion near the skull base. High-resolution distortion-free DWI should be more suitable. We apply a recently developed fast point-spread-function encoded EPI on pituitary imaging. It generates high-resolution distortion-free DWI, in which the signals of the microadenoma and the RCCs are hyperintense and hypointense, respectively. This study shows the potential of this technique to distinguish between PAs and RCCs.

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