MRI examinations usually contain multi-contrast images, which may share redundant information. For example, T2w-FLAIR contrast relies on the property of T2 relaxation and water component of the tissue, which also present in T2- and diffusion-weighted images. T2w-FLAIR acquisition is usually lengthy due to the long inversion time. In this study, point-spread-function (PSF) encoded EPI (PSF-EPI) DWI and T2-weighted images were used to generate T2w-FLAIR images by taking the advantages of high-resolution and distortion-free of PSF-EPI. This method has the potential to improve the acquisition efficiency of MRI.