In this study, we aimed to investigate whether intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) techniques can be used to evaluate the pathological grade of clear cell renal cell carcinoma (ccRCC) patients preoperatively. As a result, the IVIM-related parameters (ADC, apparent diffusion coefficient; D, true diffusivity) and DKI-related parameters (MD, mean diffusivity; MK, mean kurtosis) have shown significant differences between low- and high-grade ccRCC(0.58±0.11 vs 0.48±0.08, 1.39±1.18 vs 0.98±0.21, 2.12±0.35 vs 1.59±0.32, 0.53±0.13 vs 1.59±0.32; p<0.05). Therefore, IVIM and DKI techniques can be used effective tools to differentiate low- and high-grade ccRCC.
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