Abstract #4590

Altered functional connectivity of the primary auditory with cognitive networks in inattentive children and adolescents with hearing loss

Jianhong Li¹, Weiwei Men², David Zhu³, and Junfang Xian¹

¹Radiology, Beijing Tongren Hospital,Capital Medical University, Beijing, China, ²Center for MRI Research, Academy for Advanced Interdisciplinary Studies, Beijing City Key Lab for Medical Physics and Engineering, Institute of Heavy Ion Physics, School of Physics, Peking University, Beijing, China, ³Radiology and Cognitive Imaging Research Center, Michigan State University, East Lansing, MI, United States

Early profound deaf children and adolescents have been reported to suffer from cognitive decline and attentional deficit. Twenty-five inattentive children and adolescents with bilateral prelingual profound deafness and 30 age- and gender- matched normal controls were recruited in this study. The resting state functional connectivity differences were analyzed between two groups. The results indicated a direct impact of early auditory deprivation on high cognitive networks. The usage of hearing aid was also found to normalize the connectivity between primary auditory cortex and attention network.

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