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Abstract #4601

Abnormal Left Atrial Performance in Children with Repair Tetralogy of Fallot using CMR Feature Tracking

Liwei Hu1, Xiaodan Zhao2, Rongzhen Ouyang1, Shuang Leng2, WeiHui Xie1, Yafeng Peng1, Xiaofen Yao1, Yong Zhang3, Ru San Tan2,4, Liang Zhong2,4, and Yumin Zhong1
1Radiology, Shanghai Children's Medical Center, Shanghai, China, 2National Heart Centre Singapore, Singapore, Singapore, 3GE Healthcare, Shanghai, China, 4Duke-NUS Medical School, National University of Singapore, Singapore, Singapore

Right ventricular (RV) and atrial (RA) dilation has been clinically observed in patients after initial repair of tetralogy of Fallot (rTOF) and is associated with adverse long-term outcomes. Due to RA and left atrial (LA) interaction, we aimed to determine the effect of RA dilation on LA performance from feature tracking cardiovascular magnetic resonance (CMR) in pediatric rTOF patients. Results revealed that LA strains and strain rates were impaired in rTOF than age- and gender-matched healthy volunteers. RA volumes are negatively associated with LA strains. These findings may suggest LA diastolic dysfunction from chronic RV and RA dilations in rTOF, even at early stage after initial repair.

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