Abstract #4623

Quiet Diffusion-weighted Imaging in Pediatric Patients with Moyamoya Disease

Satoshi Nakajima¹, Yasutaka Fushimi¹, Tomohisa Okada², Gosuke Okubo¹, Yusuke Yokota¹, Sonoko Oshima¹, Sayo Otani¹, Azusa Sakurama¹, Krishna Pandu Wicaksono¹, and Kaori Togashi¹

¹Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, ²Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan

Diffusion-weighted imaging (DWI) is an essential MR sequence for evaluating pediatric patients with moyamoya disease (MMD). Acoustic noise associated with DWI may lead to motion artifact. Compared with conventional DWI (cDWI), quiet DWI (qDWI) is considered less noisy and able to keep children more relaxed and stable. We evaluated the advantages of qDWI compared with cDWI in pediatric MMD patients. Compared with cDWI, qDWI induced fewer artifacts in sedated pediatric MMD patients, whereas in unsedated patients, the frequencies of qDWI- and cDWI-induced artifacts were similar. qDWI and cDWI had the same performance for detecting restricted diffusion.

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