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Abstract #4688

Correlation analysis between amide proton transfer weighted and blood flow status in infarct core of patients with subacute ischemic stroke

Yuhan Jiang1, Yanwei Miao1, Liangjie Lin2, Zhiwei Shen2, Peipei Chang1, Yiwei Che1, Ailian Liu1, Qingwei Song1, and Jiazheng Wang2
1the First Affiliated Hospital of Dalian Medical University, Dalian, China, Dalian, China, 2Philips Healthcare, Beijing, China, Beijing, China

Amide proton transfer weighted (APTw) MR imaging enables detections of metabolite and pH value changes, while the arterial spin label (ASL) imaging can assess hemodynamic changes in brain tissue after cerebral infarction. This study aimed to evaluate correlation between APT-related metabolic changes and blood flow status in the infarct core of patients with subacute ischemic stroke by APTw and ASL MR techniques. Significant correlations of APT to apparent diffusion coefficient (ADC) and cerebral blood flow (CBF) values in the infarct region were observed.

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