Abstract #4688

Correlation analysis between amide proton transfer weighted and blood flow status in infarct core of patients with subacute ischemic stroke

Yuhan Jiang¹, Yanwei Miao¹, Liangjie Lin², Zhiwei Shen², Peipei Chang¹, Yiwei Che¹, Ailian Liu¹, Qingwei Song¹, and Jiazheng Wang²

¹the First Affiliated Hospital of Dalian Medical University, Dalian, China, Dalian, China, ²Philips Healthcare, Beijing, China, Beijing, China

Amide proton transfer weighted (APTw) MR imaging enables detections of metabolite and pH value changes, while the arterial spin label (ASL) imaging can assess hemodynamic changes in brain tissue after cerebral infarction. This study aimed to evaluate correlation between APT-related metabolic changes and blood flow status in the infarct core of patients with subacute ischemic stroke by APTw and ASL MR techniques. Significant correlations of APT to apparent diffusion coefficient (ADC) and cerebral blood flow (CBF) values in the infarct region were observed.

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