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Abstract #4693

3D automatic segmentation analysis of pituitary in children with precocious puberty

Hang Qu1, Yu Pan1, RuiHong Chen1, Weiqiang Dou2, Weiyin Vivian Liu2, and Wei Wang1
1The Affiliated Hospital of Yangzhou University, Yangzhou, China, 2GE Healthcare, MR Research China, Beijing, P.R. China, Beijing, China

To explore changes of pituitary morphology in precocious children.An in-house software based on Matlab platform was used to obtain pituitary morphological measurements. In this research the height of the pituitary in the CPP group was higher than that in the PPP group and the normal group. The pituitary volume of the CPP group was larger than that of the normal group.Pituitary volume and surface area of CCP group were positively correlated with hormone metabolism levels. The height of pituitary gland is still the index of differential diagnosis, however pituitary volume and surface area have better correlation with hormone level.

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