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Abstract #4695

R2* mapping in children with attention deficit hyperactivity disorder: a whole-brain analysis

Yingqian Chen1, Shu Su1, Long Qian2, Yan Dai1, Miao Fan1, Hongyu Zhang3, and Zhiyun Yang1
1Department of Radiology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, 2MR Research, GE Healthcare, Beijing, China, 3Department of Pediatric, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

Attention deficit/hyperactivity disorder (ADHD) might associate with the iron deficiency, but few studies reported on the correlation between brain iron level and the severity of illness. To address whether the changes of iron deposition are correlated with the cognitive function deficits in ADHD, the R2* mapping were applied in current study. The results indicated that the correlations between the R2* value and the symptom severity of ADHD were found in in brain regions within the basal ganglia region, temporal lobe and occipital lobe, which also indicated that R2* mapping might have the potential efficacy in the auxiliary diagnosis of ADHD.

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