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Abstract #4759

USPIO-Enhanced Imaging of Mediastinal Lymph Nodes in Esophageal Cancer with Sparse Radial MRI

Ivo Maatman1, Didi de Gouw2, John Hermans1, Kai Tobias Block3, Marnix Maas1, and Tom Scheenen1
1Department of Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, Netherlands, 2Department of Surgery, Radboud university medical center, Nijmegen, Netherlands, 3Department of Radiology, New York University, New York, NY, United States

Clinical imaging techniques are unable to outline metastatic spread of esophageal cancer to nearby lymph nodes. This deficiency is predominantly due to significant motion in the upper abdomen. We radially acquired MRI data with a contrast agent of USPIO nanoparticles to image the lymph nodes of an esophageal cancer patient. After retrospective gating the data into motion phases we created images with a compressed sensing reconstruction. We also acquired traditional multi-gradient echo sequences in breath-hold and apnea. The radially acquired, compressed sensing reconstructed and motion-gated images appear of similar diagnostic quality to those obtained with traditional modalities.

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