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Abstract #4833

Magnetic resonance imaging in the evaluation of dose distribution of a radiotherapy plan for brain metastases

Jianxin Ren1, Guanzhong Gong1, Xinsen Yao1, Weiqiang Dou2, Weiyin Vivian Liu2, and Yong Yin1
1Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China, 2GE Healthcare, MR Research China, Beijing, China

In this study, a protocol of pseudo CT values obtained on MRI for treatment planning was proposed. The tissue or organ-specific CT values in representation of the electron density acquired from 35 patients with brain metastases were assigned to MRI. The dose distribution was recalculated, and the dosimetric differences between a new plan and an original plan were compared. The results showed that the dose distribution errors were basically controlled under 2.0% with pseudo CT values to bones, cavities and soft tissues, and lowered than 1.5% with pseudo CT values to different tissues and organs.

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