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Abstract #4835

MRI based measurement of pancreas motion reduction with an MR- and particle therapy compatible abdominal corset

Sergej Schneider1,2,3, Sarah Stefanowicz1,3,4, Christina Jentsch1,4,5, Fabian Lohaus4, Chiara Valentini4, Esther G. C. Troost1,3,4,5,6, and Aswin L. Hoffmann1,3,4
1Oncoray – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany, 2Technische Universität Dresden, Carl Gustav Carus Faculty of Medicine, Dresden, Germany, 3Institute of Radiooncology-OncoRay, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany, 4Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, 5National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany, German Cancer Research Center (DKFZ), Heidelberg, Germany, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, and Helmholtz Association / Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany, 6German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany

Particle beam therapy (PBT) is extremely sensitive to patient setup uncertainties and anatomical variations prior to and during dose delivery. Organ motion mitigation strategies are hence required to deliver the dose with high precision and accuracy. In this study, an MR- and PBT-compatible patient-individualized abdominal corset was developed and tested in 9 patients with abdominal cancer for its efficacy to reduce respiratory-induced motion. Pancreas motion was analyzed with and without corset by means of orthogonal 2D-cine and 4D-MRI.

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