Abstract #4835

MRI based measurement of pancreas motion reduction with an MR- and particle therapy compatible abdominal corset

Sergej Schneider^1,2,3, Sarah Stefanowicz^1,3,4, Christina Jentsch^1,4,5, Fabian Lohaus⁴, Chiara Valentini⁴, Esther G. C. Troost^1,3,4,5,6, and Aswin L. Hoffmann^1,3,4

¹Oncoray – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany, ²Technische Universität Dresden, Carl Gustav Carus Faculty of Medicine, Dresden, Germany, ³Institute of Radiooncology-OncoRay, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany, ⁴Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, ⁵National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany, German Cancer Research Center (DKFZ), Heidelberg, Germany, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, and Helmholtz Association / Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany, ⁶German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany

Particle beam therapy (PBT) is extremely sensitive to patient setup uncertainties and anatomical variations prior to and during dose delivery. Organ motion mitigation strategies are hence required to deliver the dose with high precision and accuracy. In this study, an MR- and PBT-compatible patient-individualized abdominal corset was developed and tested in 9 patients with abdominal cancer for its efficacy to reduce respiratory-induced motion. Pancreas motion was analyzed with and without corset by means of orthogonal 2D-cine and 4D-MRI.

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