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Abstract #0021

Visualization of Post-Infarction Cardiac Tissue Remodeling at 7T using T2* contrast: Longitudinal Study in a Pig Myocardial Infarction Model

Maxim Terekhov1, David Lohr1, Michael Hock1, Maya Bille1, Steffen Baltes1, Ibrahim A. Elabyad1, Florian Schnitter2, Julia Aures1, Theresa Reiter2, Wolfgang Bauer1,2, Ulrich Hofmann2, and Laura M. Schreiber1
1Chair of Molecular and Cellular Imaging, University Hospital Würzburg, Comprehensive Heart Failure Center, Wuerzburg, Germany, 2Department of Internal Medicine I, Cardiology, University Hospital Würzburg, Wuerzburg, Germany

Cardiac MRI at 7T is a developing methodology capable to increase physical sensitivity and spatial resolution of the cardiac MR-images. T2*-quantification at 7T is of particular interest because it is highly sensitive to cardiac microstructure and has the potential to improve data quality on cardiac tissue remodeling in both acute and chronic cardiac diseases compared to clinical B0-field. In this work, we present the results of a pilot study correlating the multi-slice T2*-data with late-gadolinium-enhancement and first-pass-perfusion results in the large animal model of myocardial infarction. 8 pigs measured prior and at three dates after inducing myocardial infarction are analyzed.

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