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Abstract #0071

Fourier-based decomposition approach for simultaneous acquisition of 1H spectra from two voxels in vivo at short echo times

Layla Tabea Riemann1, Christoph Stefan Aigner1, Ralf Mekle2, Sebastian Schmitter1,3, Bernd Ittermann1, and Ariane Fillmer1
1Physikalisch-Technische Bundesanstalt (PTB), Braunschweig und Berlin, Germany, 2Center for Stroke Research Berlin, Charité Universitätsmedizin, Berlin, Germany, 3Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

In this work, a Fourier-based technique for 1H MR spectroscopy based on split-slice-GRAPPA is introduced to decompose simultaneously acquired dual-voxel data. In contrast to the existing sensitivity-map-based approach, this technique does not need any additional image acquisitions. The autocalibration lines are derived by additional low SNR spectral data. 2SPECIAL was used to simultaneously acquire data from two voxels at short echo times. The proposed decomposition algorithm was first validated in a multi-compartment phantom, and its application was then demonstrated at 7T in vivo.

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