Abstract #0071

Fourier-based decomposition approach for simultaneous acquisition of 1H spectra from two voxels in vivo at short echo times

Layla Tabea Riemann¹, Christoph Stefan Aigner¹, Ralf Mekle², Sebastian Schmitter^1,3, Bernd Ittermann¹, and Ariane Fillmer¹

¹Physikalisch-Technische Bundesanstalt (PTB), Braunschweig und Berlin, Germany, ²Center for Stroke Research Berlin, Charité Universitätsmedizin, Berlin, Germany, ³Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

In this work, a Fourier-based technique for ¹H MR spectroscopy based on split-slice-GRAPPA is introduced to decompose simultaneously acquired dual-voxel data. In contrast to the existing sensitivity-map-based approach, this technique does not need any additional image acquisitions. The autocalibration lines are derived by additional low SNR spectral data. 2SPECIAL was used to simultaneously acquire data from two voxels at short echo times. The proposed decomposition algorithm was first validated in a multi-compartment phantom, and its application was then demonstrated at 7T in vivo.

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