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Abstract #0121

Visualizing the cerebellar cortical layers with prospective motion correction

Nikos Priovoulos1, Mads Andersen2, Vincent O Boer3, and Wietske van der Zwaag1
1Spinoza Center, Amsterdam, Netherlands, 2Philips Healthcare, Copenhagen, Denmark, 3Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Hvidovre, Denmark

The cerebellar cortical microstructure is important for several functions, like motor control, but remain largely underexplored in vivo due to its small thickness. Here, we combined a susceptibility-weighted acquisition with in-plane resolution of just 0.2x0.2mm2 at 7Tesla along with a fat-navigator-based prospective motion correction. Using this setup, the cerebellar layers could be seen in the phase images of all 4 MRI-naive participants. Our results show that the cerebellar layers can be consistently visualized opening new neuroscientific and clinical dimensions.

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