Quantitative T1, T2, T2* and fat fraction maps are promising imaging biomarkers for the assessment and follow-up of liver disease, while T1⍴ mapping has been reported to be a valuable tool for contrast-free assessment of liver fibrosis. However, these multiple scans are usually performed sequentially during separate breath-holds, leading to long scan times and potentially mis-registered maps. In this study we propose an 8-echo T1, T2 and T1⍴ prepared liver MRF sequence that allows for quantitative T1, T2, T2*, T1⍴ and FF liver tissue characterization in a single breath-hold scan. The proposed approach has been investigated in healthy subjects.
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