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Abstract #0171

Simultaneous comprehensive T1, T2, T2*, T1Ρ and Fat Fraction characterization with Magnetic Resonance Fingerprinting

Carlos Velasco1, Gastao Cruz1, René M. Botnar1, and Claudia Prieto1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Quantitative T1, T2, T2* and fat fraction maps are promising imaging biomarkers for the assessment and follow-up of liver disease, while T1⍴ mapping has been reported to be a valuable tool for contrast-free assessment of liver fibrosis. However, these multiple scans are usually performed sequentially during separate breath-holds, leading to long scan times and potentially mis-registered maps. In this study we propose an 8-echo T1, T2 and T1⍴ prepared liver MRF sequence that allows for quantitative T1, T2, T2*, T1⍴ and FF liver tissue characterization in a single breath-hold scan. The proposed approach has been investigated in healthy subjects.

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