Abstract #0175

Coil Design Impacts Image Encoding: Optimized 64-Channel Array Configurations for Diffusion-Weighted Imaging in 3T Cardiac MRI

Robin Etzel^1,2, Choukri Mekkaoui³, Ekaterina S Ivshina⁴, Alina Scholz¹, Markus W May¹, Nicolas Kutscha¹, Matthäus Poniatowski¹, Chaimaa Chemlali¹, Anpreet Ghotra¹, Sam-Luca JD Hansen¹, Timothy G Reese³, Lawrence L Wald³, Andreas H Mahnken², and Boris Keil¹

¹Institute of Medical Physics and Radiation Protection, Department of Life Science Engineering, TH Mittelhessen University of Applied Sciences, Giessen, Germany, ²Philipps-University of Marburg, Department of Diagnostic and Interventional Radiology, Marburg, Germany, ³Harvard Medical School, Massachusetts General Hospital, Department of Radiology, A.A. Martinos Center for Biomedical Imaging, Boston, MA, United States, ⁴Princeton University, Princeton, NJ, United States

To determine the optimum configuration of a 64-channel array coil for highly accelerated in vivo cardiac diffusion-weighted imaging (DWI), the encoding capability and sensitivity of three 64-channel arrays were designed, constructed, and evaluated. Simultaneous multi-slice (SMS) acceleration enabled enhanced efficiency of the diffusion acquisitions. The array configuration with a non-uniformly distributed loop density showed the most favorable cardiac imaging performance in both SNR and SMS encoding power. Cardiac DWI of a healthy volunteer mirrors the findings from phantom evaluation and testing. Such technically advanced coils are an important component for translation of cardiac DWI to clinical settings.

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