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Abstract #0190

Gadolinium-free Multi-contrast 3D whole-heart MRI for improved anatomical assessment in patients with Congenital Heart Disease 

Anastasia Fotaki1,2, Karl Kunze1, Harith Alam2, Yasodhara Emmanuel2, Alessandra Frigiola2, Kuberan Pushparajah1,2, René Botnar1, and Claudia Prieto1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Adult Congenital Heart Disease Department, Guy’s and St Thomas’s Hospital, London, United Kingdom

Bright- and black-blood MRI sequences provide complementary information on anatomical assessment for patients with Congenital Heart Disease(CHD).A free-breathing 3D whole-heart sequence (MTC-BOOST) has been recently proposed for simultaneous bright and black-blood high quality depiction of cardiac and vascular structures waiving the need for contrast agent injection. In this study, we clinically validated this sequence in a cohort of 35 patients with CHD against the conventional T2-prep bSSFP sequence. Quantitative and qualitative image quality assessment demonstrates that MTC-BOOST enhances pulmonary venous depiction, mitigates flow-related artefacts and has comparable image quality for intracardiac and vascular structures, promising potential integration into clinical workflow.

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