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Abstract #0238

Quantitative Sodium MRI of the Human Kidney at 7T Applying Respiratory Sorting

Anna K. Scheipers1, Johanna Lott1, Armin M. Nagel1,2, Peter Bachert1, Mark E. Ladd1, and Tanja Platt1
1Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 2University Hospital Erlangen, Institute of Radiology, Friedrich‐Alexander‐Universität Erlangen‐Nürnberg (FAU), Erlangen, Germany

Sodium (23Na) plays an important role in many cellular processes, making it an interesting nuclei to investigate using MRI. Low in-vivo signals and short relaxation times require high magnetic field strengths, dedicated hardware and pulse sequences as well as correction methods to obtain reliable tissue sodium concentrations. Therefore we compare the influence of different correction methods on 23Na concentration investigations in the human kidney and validate our methods with phantom measurements. We employ retrospective respiratory self‐gating for the quantitative 23Na images as well as for the acquired B1+ maps to reduce the influence of image blurring due to motion artifacts.

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