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Abstract #0254

Quantitative MRI measurements of ectopic fat and body composition as predictors of T2D remission after bariatric surgery

Naomi S Sakai1, Kusuma Chaiyasoot1, Alan Bainbridge2, Margaret Hall-Craggs1, Rachel L Batterham1, and Stuart A Taylor1
1University College London, London, United Kingdom, 2University College London Hospitals, London, United Kingdom

Bariatric surgery can lead to rapid and substantial improvements in glycaemic control, often before significant weight loss has occurred. However, a proportion of patients do not achieve type 2 diabetes (T2D) remission after surgery despite significant post-surgical weight loss. Ectopic fat deposition and alterations in body composition are implicated in T2D pathoaetiology. Quantitative MRI (qMRI) can provide non-invasive measurements of ectopic organ fat and body composition which may have roles as predictors of T2D remission after bariatric surgery. This study aimed to assess the relationship between T2D remission status and qMRI-derived measurements of ectopic fat and body composition.

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