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Abstract #0281

xSPEN spectroscopy: a self-navigated fast chemical shift encoded echo planar imaging acquisition

Ke Dai1, Hao Chen1, Hongda Shao2, Jianjun Liu2, and Zhiyong Zhang1
1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, 2Departments of Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

xSPEN is a single-shot echo-planar imaging-based MRI approach with exceptional resilience to chemical shifts and field inhomogeneities. We introduce a time increasing (t1) evolution as chemical shift encoding to fast obtain multiple-voxel spectroscopy. The new method endows a 2D self-navigated motion correction and a unique J-decoupled spectrum by splitting the t1 evolution into τ-t1/2 and t1/2 on two sides of π pulse, which results a constant-τ J coupling evolution. We present in vitro results, demonstrating an alternative fast MRSI and increasing chemical shift separation and detection with the robustness to the in-plane motion and the unique J-decoupled spectrum capability.

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