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Abstract #0398

Gradient waveform design for cross-term-compensated diffusion MRI: Demonstration of tensor-valued encoding in phantom and simulations

Filip Szczepankiewicz1 and Jens Sjölund2
1Clinical Sciences Lund, Lund University, Lund, Sweden, 2Department of Information Technology, Uppsala University, Uppsala, Sweden

Diffusion weighted imaging is perturbed by the presence of background gradients, or so-called 'cross-terms,' causing bias in estimated parameters and fiber orientations. In this work, we present a novel gradient waveform design that removes the cross-term sensitivity entirely. This design is valuable for diffusion MRI methods that are otherwise corrupted by background gradients, and it also facilitates arbitrary sequence timing, b-tensor shapes and suppression of concomitant gradient effects.

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