Abstract #0424

Motion-insensitive DTI of Kidney using Prospective Acquisition Motion Correction Triggering

Arun Joseph^1,2,3, Laila-Yasmin Mani⁴, Tom Hilbert^5,6,7, Thomas Benkert⁸, Tobias Kober^5,6,7, Bruno Vogt⁴, and Peter Vermathen³

¹Advanced Clinical Imaging Technology, Siemens Healthcare AG, Bern, Switzerland, ²Translational Imaging Center, Sitem-Insel, Bern, Switzerland, ³Departments of Radiology and Biomedical Research, University of Bern, Bern, Switzerland, ⁴Department of Nephrology and Hypertension, University Hospital Bern, Inselspital, Bern, Switzerland, ⁵Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ⁶Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, ⁷LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁸Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany

Diffusion tensor imaging (DTI) of the kidney provides important functional information such as diffusion and micro-perfusion of the tissue and additionally estimates anisotropic diffusion of water in renal tubuli. However, these measurements are highly sensitive to respiration-induced motion artifacts which bias the obtained functional information. Here, we propose to use prospective acquisition motion correction (PACE) in combination with free-breathing acquisitions for motion-insensitive diffusion measurements of the kidney. A preliminary qualitative and quantitative validation is performed on healthy subjects comparing results from conventional respiratory-triggered to PACE-triggered DTI.

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