Abstract #0469

Regulating labeling efficiency in arterial spin labeling using a multi-coil B0 shim array: Application to territory mapping

Lincoln Craven-Brightman¹, Yulin Chang², Thomas Witzel³, Nicolas S. Arango⁴, Meher R. Juttukonda^1,5, Luis Hernandez-Garcia⁶, Marta Vidorreta⁷, John A. Detre^8,9, Lawrence L. Wald^5,10, and Jason Stockmann^5,10

¹Massachusetts General Hospital, Charlestown, MA, United States, ²Siemens Medical Solutions USA, Inc., Malvern, PA, United States, ³Qbio Inc, San Carlos, CA, United States, ⁴Dept. of Electrical Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁵Harvard Medical School, Boston, MA, United States, ⁶Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States, ⁷Siemens, S.A., Madrid, Spain, ⁸Neurology, University of Pennsylvania, Philadelphia, PA, United States, ⁹Radiology, University of Pennsylvania, Philadelphia, PA, United States, ¹⁰A.A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States

We apply dynamic local B0 field control with a multi-coil (MC) shim array to improve ASL labeling. Labeling efficiency can be regulated by dynamically shimming the labeling plane during a pCASL tagging pulse train. We demonstrate this capability through territory mapping with an unspecialized MC head shim array – Through shimming, we shift target arteries relative to the labeling pulse bandwidth. Implementation takes less than 10 minutes during a scan, without previous subject information. We also simulate the improvement possible with a specialized MC neck shim array, which enables regulation in more inferior labeling planes and higher field control efficiency.

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