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Abstract #0469

Regulating labeling efficiency in arterial spin labeling using a multi-coil B0 shim array: Application to territory mapping

Lincoln Craven-Brightman1, Yulin Chang2, Thomas Witzel3, Nicolas S. Arango4, Meher R. Juttukonda1,5, Luis Hernandez-Garcia6, Marta Vidorreta7, John A. Detre8,9, Lawrence L. Wald5,10, and Jason Stockmann5,10
1Massachusetts General Hospital, Charlestown, MA, United States, 2Siemens Medical Solutions USA, Inc., Malvern, PA, United States, 3Qbio Inc, San Carlos, CA, United States, 4Dept. of Electrical Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States, 5Harvard Medical School, Boston, MA, United States, 6Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States, 7Siemens, S.A., Madrid, Spain, 8Neurology, University of Pennsylvania, Philadelphia, PA, United States, 9Radiology, University of Pennsylvania, Philadelphia, PA, United States, 10A.A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States

We apply dynamic local B0 field control with a multi-coil (MC) shim array to improve ASL labeling. Labeling efficiency can be regulated by dynamically shimming the labeling plane during a pCASL tagging pulse train. We demonstrate this capability through territory mapping with an unspecialized MC head shim array – Through shimming, we shift target arteries relative to the labeling pulse bandwidth. Implementation takes less than 10 minutes during a scan, without previous subject information. We also simulate the improvement possible with a specialized MC neck shim array, which enables regulation in more inferior labeling planes and higher field control efficiency.

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