Meeting Banner
Abstract #0505

A free-running cardiac T1* mapping sequence for quantifying dynamic changes in myocardial T1* at rest and physiological exercise

Rui Guo1, Haikun Qi2, Xiaoying Cai1,3, Selcuk Kucukseymen1, Hassan Haji-Valizadeh1, Jennifer Rodriguez1, Amanda Paskavitz1, Patrick Pierce1, Beth Goddu1, Richard B. Thompson4, and Reza Nezafat1
1Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, BOSTON, MA, United States, 2School of Biomedical Engineering and Imaging Sciences, London, United Kingdom, 3Siemens Medical Solutions USA, Inc, Boston, MA, United States, 4University of Alberta, Department of Biomedical Engineering, Edmonton, MA, Canada

In this study, we developed a free-running cardiac T1* mapping sequence (DELTA) for quantifying the dynamic changes in myocardial T1* in response to physiological exercise. DELTA adopts continuous radial acquisition, self-navigation, and adaptive acquisition window to address the challenges associated with high heart rate and deep breathing after exercise. Phantom T1* by DELTA was heart-rate insensitive and had good repeatability. In vivo T1* among multiple measurements had little variation and comparable precision with MOLLI5(3)3 T1*.In the stress/rest studies, T1* reactivity was larger during the first scan after exercise and gradually reduced along the duration of post-exercise.

This abstract and the presentation materials are available to members only; a login is required.

Join Here