Quantitative cardiac perfusion requires reliable dynamic measurement of the contrast agent concentration in both myocardium and blood. Ungated methods offer immunity to poor ECG signals, acquire multiple cardiac phases and have been shown to achieve comparable contrast-to-noise as saturation recovery based methods. However, blood flow and cardiac motion can interrupt the steady-state and result in the calculation of inaccurate contrast agent concentrations. These errors in perfusion quantification can be avoided using a proposed Flow and Motion Insensitive Steady State (FAMISS) technique.
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