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Abstract #0564

In vivo Two-photon Magnetic Resonance Imaging of Human Brain at 3T

Jianshu Chi1, Victor Han1, and Chunlei Liu1,2
1Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, United States, 2Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, United States

We are exploring in vivo brain imaging with two-photon excitation on a 3T scanner. To do that, we built a customized coil that is large enough to fit a standard birdcage transceiver coil inside of it. The resulting two-photon gradient-echo brain images excited using a 25.5 kHz z-axis RF were overall similar to standard single-photon images with equivalent parameters. Interestingly, we observed some slight differences in tissue contrast whose cause are being investigated.

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