Abstract #0564

In vivo Two-photon Magnetic Resonance Imaging of Human Brain at 3T

Jianshu Chi¹, Victor Han¹, and Chunlei Liu^1,2

¹Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, United States, ²Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, United States

We are exploring in vivo brain imaging with two-photon excitation on a 3T scanner. To do that, we built a customized coil that is large enough to fit a standard birdcage transceiver coil inside of it. The resulting two-photon gradient-echo brain images excited using a 25.5 kHz z-axis RF were overall similar to standard single-photon images with equivalent parameters. Interestingly, we observed some slight differences in tissue contrast whose cause are being investigated.

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