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Abstract #0595

One-year follow-up of functional lung MRI in children with cystic fibrosis

Corin Willers1, Lukas Maager1, Bettina S. Frauchiger1, Kathryn Ramsey1, Grzegorz Bauman2,3, Orso Pusterla2,3, Oliver Bieri2,3, and Philipp Latzin1
1Division of Pediatric Respiratory Medicine, Department of Pediatrics,, Inselspital, Bern University Hospital, University of Bern, Switzerland, Bern, Switzerland, 2Division of Radiological Physics, Department of Radiology, University of Basel Hospital Basel, Basel, Switzerland, Basel, Switzerland, 3Department of Biomedical Engineering, University of Basel, Basel, Switzerland, Basel, Switzerland

Matrix Pencil MRI in cystic fibrosis is a sensitive and promising technique to monitor progression of lung disease, and is especially well-suited for children. In this work, we investigate the agreement between changes in functional lung MRI and in lung function tests during a 1-year follow-up period. We demonstrate the benefit of imaging to interpret changes in lung function correctly.

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