Abstract #0595

One-year follow-up of functional lung MRI in children with cystic fibrosis

Corin Willers¹, Lukas Maager¹, Bettina S. Frauchiger¹, Kathryn Ramsey¹, Grzegorz Bauman^2,3, Orso Pusterla^2,3, Oliver Bieri^2,3, and Philipp Latzin¹

¹Division of Pediatric Respiratory Medicine, Department of Pediatrics,, Inselspital, Bern University Hospital, University of Bern, Switzerland, Bern, Switzerland, ²Division of Radiological Physics, Department of Radiology, University of Basel Hospital Basel, Basel, Switzerland, Basel, Switzerland, ³Department of Biomedical Engineering, University of Basel, Basel, Switzerland, Basel, Switzerland

Matrix Pencil MRI in cystic fibrosis is a sensitive and promising technique to monitor progression of lung disease, and is especially well-suited for children. In this work, we investigate the agreement between changes in functional lung MRI and in lung function tests during a 1-year follow-up period. We demonstrate the benefit of imaging to interpret changes in lung function correctly.

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