Meeting Banner
Abstract #0600

Identifying Diffuse Intrinsic Pontine Glioma (DIPG) Subtypes via Radiomic Approaches

Silu Zhang1, Zoltan Patay1, Bogdan Mitrea2, Angela Edwards1, Lydia McColl Makepeace1, and Matthew A. Scoggins1
1Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, TN, United States, 2Activ Surgical, Boston, MA, United States

Diffuse intrinsic pontine glioma (DIPG) is a pediatric brain tumor with very poor prognosis. In this study, we identify two subtypes of DIPG based on radiomic features. The two subtypes show a significant difference in survival rates. Subtype 1 has a mean progression-free survival (PFS) and overall survival (OS) of 8.9 and 12.7 months, respectively. Subtype 2 has a mean PFS and OS of 5.7 and 9.1 months, respectively. Our results suggest that shape features and intensity features extracted from FLAIR and T1-post contrast predict the prognosis of DIPG.

This abstract and the presentation materials are available to members only; a login is required.

Join Here