In this study, we optimized a Faster R-CNN algorithm through constraining anchor boxes generated by Region Proposal Network (RPN) based on prior knowledge, and evaluated the feasibility of the optimized model in detecting and differentiating Hashimoto's thyroiditis (HT) from papillary thyroid microcarcinomas (PTMC) based on high b-value (2000 sec/mm2) diffusion-weighted images that acquired with readout segmentation of long variable echo-trains (RESOLVE) sequence. The study indicated that our model based on high b-value (2000 sec/mm2) DWI images demonstrated great potential as a new inspection tool in the diagnosis of benign and malignant thyroid micronodules.
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