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Abstract #0625

Joint 3D motion-field and uncertainty estimation at 67Hz on an MR-LINAC

Niek RF Huttinga1, Tom Bruijnen1, Cornelis AT van den Berg1, and Alessandro Sbrizzi1
1Department of Radiotherapy, Computational Imaging Group for MR therapy & Diagnostics, University Medical Center Utrecht, Utrecht, Netherlands

We present a probabilistic framework to perform simultaneous real-time 3D motion estimation and uncertainty quantification. We extend our preliminary work to a realistic prospective in-vivo setting, and demonstrate it on an MR-LINAC. The acquisition+processing time for 3D motion-fields is around 15ms, yielding a 67Hz frame-rate. Results indicate high quality predictions, and uncertainty estimates that could be used for real-time quality assurance during MR-guided radiotherapy on an MR-LINAC.

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