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Abstract #0838

Rapid T2-DIADEM Echo-Planar Imaging as an Alternative to T2-FSE: A Clinical Feasibility Study

Myung-Ho In1, Norbert G Campeau1, John III Huston1, Zijing Dong2,3, Kawin Setsompop4,5, Daehun Kang1, Uten Yarach6, Yunhong Shu1, Joshua D Trzasko1, and Matt A Bernstein1
1Department of Radiology, Mayo Clinic, Rochester, MN, United States, 2A. A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States, 3Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, 4Department of Radiology, Stanford University, Stanford, CA, United States, 5Stanford University, Stanford, CA, United States, 6Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand

Rapid high-resolution echo-planar-imaging (EPI) with improved image quality could conceivably be utilized as a high-speed alternative to conventional T2-weighted fast-spin-echo imaging (T2-FSE). A variant of multi-shot EPI, DIADEM (distortion-free imaging: a double encoding method), was recently described (5) and shown to yield high quality, high resolution images free of spatial distortion. In this work, a T2-weighted DIADEM pulse sequence was optimized with self-calibrated, tilted-CAIPI reconstruction scheme and then comparatively evaluated to T2-FSE images of the brain in 24 human subjects by two neuroradiologists.

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