Abstract #0838

Rapid T2-DIADEM Echo-Planar Imaging as an Alternative to T2-FSE: A Clinical Feasibility Study

Myung-Ho In¹, Norbert G Campeau¹, John III Huston¹, Zijing Dong^2,3, Kawin Setsompop^4,5, Daehun Kang¹, Uten Yarach⁶, Yunhong Shu¹, Joshua D Trzasko¹, and Matt A Bernstein¹

¹Department of Radiology, Mayo Clinic, Rochester, MN, United States, ²A. A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States, ³Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, ⁴Department of Radiology, Stanford University, Stanford, CA, United States, ⁵Stanford University, Stanford, CA, United States, ⁶Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand

Rapid high-resolution echo-planar-imaging (EPI) with improved image quality could conceivably be utilized as a high-speed alternative to conventional T2-weighted fast-spin-echo imaging (T2-FSE). A variant of multi-shot EPI, DIADEM (distortion-free imaging: a double encoding method), was recently described (5) and shown to yield high quality, high resolution images free of spatial distortion. In this work, a T2-weighted DIADEM pulse sequence was optimized with self-calibrated, tilted-CAIPI reconstruction scheme and then comparatively evaluated to T2-FSE images of the brain in 24 human subjects by two neuroradiologists.

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