Abstract #0845

Simultaneous anatomical, pathological and T2 quantitative knee imaging with 3D submillimeter isotropic resolution using MIXTURE

Takayuki Sakai^1,2, Masami Yoneyama³, Atsuya Watanabe^4,5, Daichi Murayama¹, Shigehiro Ochi¹, Shuo Zhang⁶, and Tosiaki Miyati⁷

¹Radiology, Eastern Chiba Medical Center, Tonage, Japan, ²Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan, ³Philips Japan, Tokyo, Japan, ⁴General Medical Services, Chiba University Graduate School of Medicine, Chiba, Japan, ⁵Orthopaedic Surgery, Eastern Chiba Medical Center, Chiba, Japan, ⁶Philips Healthcare, Hamburg, Germany, ⁷Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan

We propose a new sequence called MIXTURE (Multi-Interleaved X-prepared TSE with inTUitive RElaxometry). MIXTURE is a 3D TSE that can set arbitrary echo times using the T2 preparation pulses, and enables several image contrasts (such as PDW, T2W) and T2 mapping by acquiring at least two echo time images. In this study, we evaluated the clinical feasibility of morphological and pathological MRI with two contrasts images and quantitative MRI with T2 mapping using MIXTURE.

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