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Abstract #0850

Diffusion Tensor Imaging and Fiber Tractography in Porcine Meniscus

Jikai Shen1, Qi Zhao1, Yi Qi1, Gary Cofer1, G. Allan Johnson1, and Nian Wang2
1Duke University, Durham, NC, United States, 2Radiology and Imaging Sciences, Indiana University, Indianapolis, IN, United States

Recently, diffusion MRI and tractography in musculoskeletal system has used to investigate the tissue microstructure, local collagen fiber alignment, and the 3D collagen network. To the best of our knowledge, nondestructively probing the local collagen fiber direction and 3D collagen fiber architecture is still limited. The water diffusion properties derived from DTI were quantified at different areas of meniscus using the proposed automatic segmentation method. Combining tractography and automatic segmentation, we were able to observe the structural connections among different areas of the meniscus.

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