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Abstract #0868

Atlas of reproducible short-range association fibers in parietal lobe by STTAR tracing and clustering

Chenying Zhao1,2, Minhui Ouyang1, and Hao Huang1,3
1Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, United States, 2Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, United States, 3Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

Short-range association fibers (SAFs) linking adjacent cortices, are dominant in connectome and altered in psychiatric disorders such as autism and schizophrenia. However, few atlases are dedicated to SAFs. Higher inter-subject variation and large amount of SAFs impede their identification with traditional methods for long-range fibers. To meet these challenges, we built the SAF atlas using STTAR (Short-range Tractography with high Throughput And Reproducibility), a novel and advanced protocol designed for SAFs. Here, we demonstrated the SAF atlas in parietal lobe, featured with reproducibly and comprehensively traced SAFs readily usable in 3D volume format in the ICBM152 space.

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