Abstract #0883

Boosting the SNR-efficiency of Free Gradient Waveform Diffusion MRI using Spiral Readouts and Ultra-Strong Gradients

Lars Mueller¹, Maryam Afzali¹, Malwina molendowska¹, Chantal M.W. Tax^1,2, Fabrizio Fasano^3,4, Suryanarayana Umesh Rudrapatna¹, and Derek K. Jones^1,5

¹CUBRIC, Cardiff University, Cardiff, United Kingdom, ²Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands, ³Siemens Healthcare Ltd, Camberly, United Kingdom, ⁴Siemens Healthcare GmbH, Erlangen, Germany, ⁵Mary McKillop Institute for Health Research, Faculty of Health Sciences, Australian Catholic University, Melbourne, Melbourne, Australia

Free gradient waveforms for diffusion MRI offer new insights in the underlying microstructure compared the classical Stejskal-Tanner linear encoding. A drawback of this approach is the prolonged echo time and thus decreased SNR. Here we present an approach to shorten the echo time by employing spiral readouts instead of echo-planar imaging and using the ultra-strong gradients of the Connectom scanner. The feasibility of this approach is demonstrated in a biomimetic phantom.

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