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Abstract #0883

Boosting the SNR-efficiency of Free Gradient Waveform Diffusion MRI using Spiral Readouts and Ultra-Strong Gradients

Lars Mueller1, Maryam Afzali1, Malwina molendowska1, Chantal M.W. Tax1,2, Fabrizio Fasano3,4, Suryanarayana Umesh Rudrapatna1, and Derek K. Jones1,5
1CUBRIC, Cardiff University, Cardiff, United Kingdom, 2Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands, 3Siemens Healthcare Ltd, Camberly, United Kingdom, 4Siemens Healthcare GmbH, Erlangen, Germany, 5Mary McKillop Institute for Health Research, Faculty of Health Sciences, Australian Catholic University, Melbourne, Melbourne, Australia

Free gradient waveforms for diffusion MRI offer new insights in the underlying microstructure compared the classical Stejskal-Tanner linear encoding. A drawback of this approach is the prolonged echo time and thus decreased SNR. Here we present an approach to shorten the echo time by employing spiral readouts instead of echo-planar imaging and using the ultra-strong gradients of the Connectom scanner. The feasibility of this approach is demonstrated in a biomimetic phantom.

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